General Anti-aging Questions
Aging is caused by a combination of NAD+ decline, oxidative stress, telomere shortening, mitochondrial dysfunction, and chronic inflammation, all of which contribute to decreased cellular function and increased damage over time.
Our RiboGEN® creates NAD+. NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme essential for energy production, DNA repair, and cellular health. Its levels decline with age, leading to mitochondrial dysfunction and decreased cell repair capacity.
Oxidative stress occurs when free radicals damage DNA, proteins, and cell membranes. Over time, this accelerates aging and increases the risk of age-related diseases. Many of our other compounds can correct these destructive causes.
Telomeres are protective caps at the ends of chromosomes. They shorten with each cell division, and when they become too short, the cell stops dividing, leading to aging, cell mutation and cellular death. Our RejuvaNOL™ CAG/CA/Oa stimulates telomere growth.
How is it possible to provide low cost but effective supplements? Why do BioBoost DR™ & BioPeak™ work so well.
Cost Efficiency: Vegetable capsules are cheap and widely available. Enhancing absorption with technologies like liposomal delivery, enteric coatings, or bioavailability enhancers (e.g., piperine) increases production costs, which may reduce profit margins or make products less competitive in a price-sensitive market.
Consumer Awareness: Many consumers are unaware of bioavailability issues or assume all supplements are equally effective. Companies capitalize on this by focusing on appealing labels, claims, or trendy ingredients rather than investing in absorption-enhancing formulations.
Regulatory Gaps: The supplement industry faces minimal regulation in many countries (e.g., FDA in the U.S. classifies supplements as food, not drugs). There’s no requirement to prove bioavailability or efficacy, so companies can market products without optimizing absorption.
Standard Practices: Basic capsules dissolve in the stomach, which is sufficient for some compounds but not others (e.g., certain vitamins, minerals, or botanicals degrade in stomach acid). The industry often sticks to this one-size-fits-all approach for simplicity and scalability, ignoring compounds that require protection or enhancement for better uptake.
Marketing Focus: Companies emphasize ingredient lists, dosages, or health claims over delivery mechanisms. Buzzwords like “high potency” or “natural” overshadow technical details like absorption, which are harder to communicate to the average consumer.
At RejuvaTech, we’re committed to maximizing the effectiveness of our premium anti-aging compounds—like nicotinamide riboside chloride, L-glutathione, spermidine 3HCl, and potent triterpenoids (cycloastragenol, asiatic acid, and oleanolic acid)—while minimizing waste and cost. Unlike many supplement companies that use basic vegetable capsules, which dissolve in the stomach and result in poor absorption, we employ cutting-edge delivery systems. Our patent-pending BioPeak™ delivery system is specifically designed for our triterpenoids, ensuring optimal absorption and efficacy. For all other compounds, our patent-pending BioBoost™ delivery system, incorporating delayed-release capsules, self-nanoemulsifying drug delivery systems (SNEDDS), and absorption enhancers, maximizes bioavailability and effectiveness.
Poor Baseline Absorption: Many anti-aging compounds have low bioavailability in standard capsules. For example, L-glutathione has only ~5% absorption, nicotinamide riboside chloride ~30%, and triterpenoids like cycloastragenol <20% due to stomach acid degradation, enzymatic breakdown, and first-pass metabolism.
Our Solution: We use delayed-release capsules to protect compounds until they reach the small intestine (pH 6-7.4), where absorption is optimal. We also incorporate enzyme inhibitors (e.g., piperine, serine-borate), permeation enhancers (e.g., sodium caprate), and efflux pump inhibitors (e.g., quercetin) for oral capsules, or SNEDDS with lipid-cyclodextrin complexes for softgels and lozenges. These increase bioavailability dramatically—up to 200% for nicotinamide riboside and spermidine, 1025% for L-glutathione, and 300-400% for triterpenoids.
Delayed-Release Capsules: These protect compounds from stomach acid, delivering them intact to the small intestine’s large surface area for better uptake. For instance, L-glutathione’s absorption jumps from 5% to 7.5% with delayed release alone.
Absorption Enhancers: Piperine boosts enzyme inhibition by 20-60%, sodium caprate enhances intestinal permeability by 50-200%, and quercetin reduces efflux by 20-50%. Together, they can triple or quadruple absorption for compounds like nicotinamide riboside (from 30% to ~90%).
SNEDDS for Triterpenoids: Our patent-pending SNEDDS softgels create nanoemulsions (50-500 nm droplets) upon contact with bodily fluids, improving solubility and uptake of lipophilic triterpenoids like cycloastragenol (from <20% to 40-50%). This targets neuronal, immune, endothelial, and regenerative cells for anti-aging benefits.
Result: Our formulations achieve 3-11x higher absorption than standard capsules, ensuring more of the active ingredient reaches your cells.
Reduced Active Ingredient Needed: Our advanced absorption technology allows smaller doses to deliver the same therapeutic benefits. For instance, our delayed-release capsule with enhanced absorption provides 216 mg of absorbed nicotinamide riboside from just 240 mg, compared to 720 mg required in a standard capsule. Similarly, a regular capsule would need 1,800 mg of glutathione to deliver only 90 mg absorbed. This efficiency lowers costs for you.
Minimized Waste: Standard capsules without our bio-enhancers waste 70-95% of active ingredients due to poor absorption, increasing costs. Our approach ensures more of the compound is absorbed by your body, reducing waste and the need for excessive dosing.
Superior Efficacy
: Smaller doses mean you pay less for the same or better results compared to standard supplements requiring massive quantities (e.g., 640 mg trans-resveratrol vs. our 160 mg for 128 mg absorbed).Sustainability: Our formulations, like RiboGEN®, DRcaps with spermidine or SNEDDS softgels, ensure compounds reach critical cells (e.g., stem, nerve, and liver cells), maximizing benefits for longevity and vitality.
In contrast, most supplement companies use basic vegetable capsules that dissolve in the stomach, losing much of the active ingredient to acid or metabolism. They prioritize low production costs and marketing over bioavailability, requiring you to take much higher doses (e.g., 1800 mg L-glutathione for just 90 mg absorbed) to achieve minimal effects. At RejuvaTech, our advanced delivery systems—backed by pharmacological research—mean you get more value, potency, and sustainability from every dose, making our products a smarter choice for your health and wallet.
What is needed to create a new anti-aging product?
At RejuvaTech, we prioritize bioavailability to ensure your body absorbs the maximum amount of active anti-aging compounds. Unlike standard supplements that use basic vegetable capsules, which lose 70-95% of ingredients to stomach acid or metabolism, we use delayed-release capsules and self-nanoemulsifying drug delivery systems (SNEDDS) with enhancers like piperine, sodium caprate, and quercetin. This boosts absorption by 300% or more (e.g., 1025% for L-glutathione, 200% for nicotinamide riboside), delivering 3-11x more active ingredient to your cells. This means smaller doses, less waste, lower costs, and stronger anti-aging benefits for you.
RiboGEN® is our flagship product, featuring pharmaceutical-grade nicotinamide riboside chloride which should be used with a delayed-release capsules. It boosts cellular NAD+ levels, providing extra energy for your cells to optimize the performance of other anti-aging compounds. Think of RiboGEN® as the foundation that supercharges compounds like L-glutathione, spermidine, or triterpenoids (e.g., cycloastragenol). Starting with RiboGEN® ensures your cells have the energy to maximize benefits like cellular repair, neuroprotection, and immune support. It’s included in a 30-day supply using size ‘0’ or ‘00’ delayed-release capsules.
Our process is simple and tailored to your needs. On our products page or individual product pages, you select the benefits you want (e.g., telomere support, inflammation reduction, or tissue repair) and choose from our range of anti-aging compounds, such as spermidine, L-glutathione, or triterpenoids like cycloastragenol. We recommend starting with RiboGEN® as the core, paired with two additional compounds. RejuvaTech handles the rest, formulating your custom blend with absorption enhancers (e.g., serine-borate, SNEDDS) and GMP-compliant excipients in size ‘0’ or ‘00’ delayed-release capsules. We also offer free prototyping to ensure the fill amount and ingredient ratios meet your specifications.
Our product pages list specific benefits for each compound, allowing you to choose based on your health goals. Examples include:
- Nicotinamide Riboside Chloride (RiboGEN®): Boosts NAD+ for cellular energy, supporting overall vitality, neuroprotection, and compound synergy (200% absorption increase, 30% to ~90%).
- L-Glutathione: Enhances detoxification, antioxidant defense, and skin health (1025% absorption increase, 5% to ~56.25%).
- Spermidine 3HCl: Promotes autophagy, cardiovascular health, and longevity (200% absorption increase, 30% to ~90%).
- Triterpenoids (Cycloastragenol, Asiatic Acid, Oleanolic Acid): Support telomere maintenance, tissue repair, and inflammation reduction (300-400% absorption increase via SNEDDS).
Select your desired benefits, and we’ll optimize the formulation to target cells like neuronal, immune, endothelial, or regenerative cells for maximum anti-aging impact.
Our free prototyping service ensures your custom supplement meets your expectations. After you select your desired benefits and compounds, we create a prototype using your chosen capsule size (‘0’ or ‘00’) and ingredients. We optimize the fill amount, incorporating absorption enhancers and excipients under GMP standards. You’ll receive a sample formulation and capsule file prototyping to review before full production, ensuring the dosage and delivery system align with your health goals.
Yes, RiboGEN® is designed to pair with other anti-aging compounds to amplify their effects. We recommend starting with RiboGEN® as the core and adding two additional compounds, such as L-glutathione and spermidine, or triterpenoids like cycloastragenol and asiatic acid. This trio maximizes benefits like cellular energy, detoxification, and telomere support. Our product pages guide you through the benefit selection, and we handle the formulation to ensure optimal absorption and potency in using delayed-release capsules.
Absolutely. All our supplements are manufactured under Good Manufacturing Practices (GMP) in facilities like those partnered with Gelita (Delasol enteric softgels) or Soft Gel Technologies. We use pharmaceutical-grade ingredients and advanced delivery systems (e.g., DRcaps, SNEDDS) to ensure safety, stability, and efficacy. Our absorption enhancers are well-studied and used at correct and effective doses to maximize benefits.
Visit our products page or individual product pages to explore the benefits of our anti-aging compounds. Select the health benefits you want (e.g., longevity, skin health, or immune support), starting with RiboGEN® and up to two additional compounds. Submit your choices, and our team will formulate your custom blend with enhanced absorption technology. It’s that easy to unlock your body’s full potential with RejuvaTech!
The coming skin care revolution.
Our revolutionary product uses a patent-pending delivery system to deliver potent triterpenoids (e.g., cycloastragenol, asiatic acid, oleanolic acid) deep into the skin’s basal and dermal layers and hair follicles. It combines nanocarriers (20-500 nm), microneedling, thermal/ultrasonic energy, and pH-responsive hydrogels to achieve over 30% better penetration than conventional methods. These triterpenoids stimulate telomerase activity, boosting collagen and elastin production to halt or reverse skin aging, offering superior rejuvenation for conditions like wrinkles, scars, and hair loss.
Unlike retinol, which primarily exfoliates and can cause irritation, our triterpenoid system targets deeper skin layers to promote true cellular regeneration. It enhances telomerase activity, supporting long-term skin elasticity and resilience, while retinol mainly addresses surface-level turnover. Our non-irritating, sustained-release formula (up to 72 hours) delivers triterpenoids with over 95% improved efficiency, providing more effective anti-aging results without the dryness or sensitivity often associated with retinol.
Our patent-pending system uses lipid-based nanocarriers (e.g., liposomes, solid lipid nanoparticles) and pH-responsive hydrogels to protect triterpenoids from degradation and ensure targeted release in the skin’s acidic microenvironments (pH 4.5-6.5). Microneedling creates microchannels (0.1-2.5 mm) for deep delivery, while thermal and ultrasonic energy enhances penetration by at least 30%. This multi-phase approach outperforms standard creams, delivering triterpenoids to regenerative cells for maximum anti-aging impact.
Yes! Triterpenoids like cycloastragenol and asiatic acid are scientifically shown to activate telomerase, which protects telomeres and promotes collagen/elastin synthesis. Our advanced delivery ensures these compounds reach the basal layer and hair follicles, stimulating cellular renewal and tissue repair. This can reduce wrinkles, improve skin elasticity, and even support hair regrowth, offering a powerful solution to reverse visible signs of aging.
Our skin rejuvenation product builds on the same commitment to high bioavailability seen in RiboGEN®, which boosts cellular NAD+ to enhance anti-aging compounds’ effects. While RiboGEN® supports internal vitality with 200-1025% better absorption, our upcoming skin product applies similar principles externally, using nanocarriers and enhancers to deliver triterpenoids with unmatched efficiency. Try RiboGEN® now to experience our cutting-edge approach and get ready for our skin innovation!